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Like most scientific disciplines, anatomy has areas of specialization. Gross anatomy is the study of the larger structures of the body, those visible without the aid of magnification (Figure 1a). Macro- means “large,” thus, gross anatomy is also referred to as macroscopic anatomy.

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The person who is trained to study human physiology is called a physiologist. Herman Boerhaave is referred to as the father of Physiology for his exemplary research and teaching during 1708.

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The use of the microscope in discovering minute, previously unknown features was pursued on a more systematic basis in the 18th century, but progress tended to be slow until technical improvements in the compound microscope itself, beginning in the 1830s with the gradual development of achromatic lenses, greatly increased that instrument’s resolving power. These technical advances enabled Matthias Jakob Schleiden and Theodor Schwann to recognize in 1838–39 that the cell is the fundamental unit of organization in all living things.

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Owing to church prohibitions against dissection, European medicine in the Middle Ages relied upon Galen’s mixture of fact and fancy rather than on direct observation for its anatomical knowledge, though some dissections were authorized for teaching purposes. In the early 16th century, the artist Leonardo da Vinci undertook his own dissections, and his beautiful and accurate anatomical drawings cleared the way for Flemish physician Andreas Vesalius to “restore” the science of anatomy with his monumental De humani corporis fabrica libri septem (1543; “The Seven Books on the Structure of the Human Body”), which was the first comprehensive and illustrated textbook of anatomy. As a professor at the University of Padua, Vesalius encouraged younger scientists to accept traditional anatomy only after verifying it themselves, and this more critical and questioning attitude broke Galen’s authority and placed anatomy on a firm foundation of observed fact and demonstration.

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Some of these organs work together and form systems that are specialised to perform a specific function or a set of functions. Collectively, these are known as organ systems.

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Muscles are specialised tissues which assist the bones in locomotion. Muscles are attached to the bones through tendons. Movement of limbs happens due to the contraction and relaxation of corresponding muscles present in that region. Joints help in the flexibility of bones, but a bone cannot be bent or stretched until a muscle acts on it. In other words, the muscles attached to that bone pulls it to the direction of movement.

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