Bria Travis July 24, 2020 Anatomy
The use of the microscope in discovering minute, previously unknown features was pursued on a more systematic basis in the 18th century, but progress tended to be slow until technical improvements in the compound microscope itself, beginning in the 1830s with the gradual development of achromatic lenses, greatly increased that instrument’s resolving power. These technical advances enabled Matthias Jakob Schleiden and Theodor Schwann to recognize in 1838–39 that the cell is the fundamental unit of organization in all living things.
When a body is dissected, its structures are cut apart in order to observe their physical attributes and their relationships to one another. Dissection is still used in medical schools, anatomy courses, and in pathology labs. In order to observe structures in living people, however, a number of imaging techniques have been developed. These techniques allow clinicians to visualize structures inside the living body such as a cancerous tumor or a fractured bone.
The need for thinner, more transparent tissue specimens for study under the light microscope stimulated the development of improved methods of dissection, notably machines called microtomes that can slice specimens into extremely thin sections. In order to better distinguish the detail in these sections, synthetic dyes were used to stain tissues with different colours.
From Vesalius’s exact descriptions of the skeleton, muscles, blood vessels, nervous system, and digestive tract, his successors in Padua progressed to studies of the digestive glands and the urinary and reproductive systems. Hieronymus Fabricius, Gabriello Fallopius, and Bartolomeo Eustachio were among the most important Italian anatomists, and their detailed studies led to fundamental progress in the related field of physiology. William Harvey’s discovery of the circulation of the blood, for instance, was based partly on Fabricius’s detailed descriptions of the venous valves.
Even to this day, scientists are newly discovering organs that were previously overlooked or have been mistakenly identified as other existing tissues. In 2018, scientists had discovered a new, body-wide organ called the Interstitium that exists right under the skin.
This is the result of humans having ancestors that began walking on their hind limbs rather than using all four limbs. Most of our anatomical insight was gained through the dissection of corpses (cadavers), and for a long time, it was the only way we could gain anatomical knowledge about the human body. It was a rather grotesque affair, but it made up the bulk of medical literature for centuries. These days, technological innovation has made it possible to explore human anatomy at a microscopic level.
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