Natalia Gentry July 17, 2020 Anatomy
Comparative anatomy, the other major subdivision of the field, compares similar body structures in different species of animals in order to understand the adaptive changes they have undergone in the course of evolution.
The need for thinner, more transparent tissue specimens for study under the light microscope stimulated the development of improved methods of dissection, notably machines called microtomes that can slice specimens into extremely thin sections. In order to better distinguish the detail in these sections, synthetic dyes were used to stain tissues with different colours. Thin sections and staining had become standard tools for microscopic anatomists by the late 19th century. The field of cytology, which is the study of cells, and that of histology, which is the study of tissue organization from the cellular level up, both arose in the 19th century with the data and techniques of microscopic anatomy as their basis.
The use of the microscope in discovering minute, previously unknown features was pursued on a more systematic basis in the 18th century, but progress tended to be slow until technical improvements in the compound microscope itself, beginning in the 1830s with the gradual development of achromatic lenses, greatly increased that instrument’s resolving power. These technical advances enabled Matthias Jakob Schleiden and Theodor Schwann to recognize in 1838–39 that the cell is the fundamental unit of organization in all living things.
This ancient discipline reached its culmination between 1500 and 1850, by which time its subject matter was firmly established. None of the world’s oldest civilizations dissected a human body, which most people regarded with superstitious awe and associated with the spirit of the departed soul. Beliefs in life after death and a disquieting uncertainty concerning the possibility of bodily resurrection further inhibited systematic study. Nevertheless, knowledge of the body was acquired by treating wounds, aiding in childbirth, and setting broken limbs. The field remained speculative rather than descriptive, though, until the achievements of the Alexandrian medical school and its foremost figure, Herophilus (flourished 300 bce), who dissected human cadavers and thus gave anatomy a considerable factual basis for the first time. Herophilus made many important discoveries and was followed by his younger contemporary Erasistratus, who is sometimes regarded as the founder of physiology.
Owing to church prohibitions against dissection, European medicine in the Middle Ages relied upon Galen’s mixture of fact and fancy rather than on direct observation for its anatomical knowledge, though some dissections were authorized for teaching purposes. In the early 16th century, the artist Leonardo da Vinci undertook his own dissections, and his beautiful and accurate anatomical drawings cleared the way for Flemish physician Andreas Vesalius to “restore” the science of anatomy with his monumental De humani corporis fabrica libri septem (1543; “The Seven Books on the Structure of the Human Body”), which was the first comprehensive and illustrated textbook of anatomy. As a professor at the University of Padua, Vesalius encouraged younger scientists to accept traditional anatomy only after verifying it themselves, and this more critical and questioning attitude broke Galen’s authority and placed anatomy on a firm foundation of observed fact and demonstration.
Human anatomy is the scientific study of the body’s structures. Some of these structures are very small and can only be observed and analyzed with the assistance of a microscope. Other larger structures can readily be seen, manipulated, measured, and weighed. The word “anatomy” comes from a Greek root that means “to cut apart.” Human anatomy was first studied by observing the exterior of the body and observing the wounds of soldiers and other injuries. Later, physicians were allowed to dissect bodies of the dead to augment their knowledge.
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